Spongioform myelinopathy in premature infants.
نویسندگان
چکیده
منابع مشابه
Neonatal spongioform myelinopathy after restricted application of hexachlorophane skin disinfectant.
At least four out of 97 low birth weight (less than 1750 g) newborn infants who had received only limited skin disinfection with 3% hexachlorophane (HCP) emulsion developed spongioform myelinopathy in association with detectable amounts of HCP in their brains. These four cases were found in a post-mortem survey of 20 out of the 27 infants who died. Another nine of these infants had detectable a...
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-brain levels of HCP varied between 0-442 and 1-204 nmol[g (0-18 and 0 49 ig/g).4 So myelinopathy in case 2 was probably attributable to HCP, despite the absence of clinical signs of toxicity. The trace level in case 1 suggests that myelinopathy was unrelated to HCP, for other causes of infantile spongioform myelinopathy are known, though none has been identified in small premature infants. Nev...
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BACKGROUND Invasive fungal infections cause excessive morbidity and mortality in premature neonates and severely ill infants. METHODS Safety and efficacy outcomes of micafungin were compared between prematurely and non-prematurely born infants <2 years of age. Data were obtained from all completed phase I-III clinical trials with micafungin that had enrolled infants (<2 years of age) that wer...
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The common anaemia in premature infants is iron deficiency anaemia, but megaloblastic anaemia can also occur and here we report three such cases. Our interest in megaloblastic anaemia was stimulated by a recent case in which megaloblastic anaemia developed when a low phenylalanine diet was being given for treatment of phenylketonuria (Royston and Parry, 1962). In the discussion of this paper Ro...
متن کاملPrebiotic oligosaccharides in premature infants.
OBJECTIVE The aim of the study was to determine the impact of increasing doses of 2 prebiotic oligosaccharides and of an "all-human diet" on the intestinal microbiota of premature infants. METHODS Twelve premature infants receiving formula feedings were randomly assigned to receive either galacto-oligosaccharide (F+GOS) or a pooled concentrated donor human milk product containing human milk o...
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ژورنال
عنوان ژورنال: BMJ
سال: 1975
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5964.175-a